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Giardia intestinalis infection as a risk factor for Cyclospora cayetanensis and Cryptosporidium...
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Giardia intestinalis infection as a risk factor for Cyclospora cayetanensis and Cryptosporidium infections in Peruvian children.
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http://www.ohsu.edu/xd/education/library/services/theses-dissertations/rights-statement.cfm
Title
Giardia
intestinalis
infection
as a
risk
factor
for
Cyclospora
cayetanensis
and
Cryptosporidium
infections
in
Peruvian
children
.
Creator.PersonalName
Ross
,
Jennifer
M
.
Thesis.Degree
M.P.H.
Thesis.Major
Public Health
Thesis.DateDegreeAwarded
May
2009
Institution
Oregon Health & Science University
School
School of Medicine
Department
Dept. of Public Health and Preventive Medicine
Thesis.Advisor/Mentor
Choi, Dongseok
Thesis.Chair
Winthrop, Kevin L.
Thesis.Committee
Cama, Vitaliano A.
Subject.Keyword
Peru
Subject.MeSH
Giardia lamblia
Cyclospora
Cryptosporidium
Population Groups
Infant
Child
Call Number
Q171 R823 2009
Description.Abstract
We
conducted
a
prospective
cohort
study
among
477
Peruvian
children
to
assess
the
frequency
of, and
risk
factors
for,
infections
with
Giardia
,
Cryptosporidium
and
Cyclospora
.
We
also
sought
to
determine
if
Giardia
infections
within
60
days
of
enrollment
into the
study
affected
the
incidence
of
Cyclospora
or
Cryptosporidium
infections
.
One-hundred
sixty
(33.5%)
of
children
had
Giardia
infection
within
the
first
sixty
days
of
observation
, and
381
(79.5%)
had at
least
one
infection
during
the
five-year
study
. The
median
episode
length
was
less
than
seven
days
,
however
,
ten
percent
of
infections
lasted
longer
than
one
year
.
Results
from the
Cox
proportional
hazards
analysis
showed
that
Giardia
increased
the
child’s
risk
for
acquiring
subsequent
infections
with
Crypsporidium
(HR
5.49
,
95%
CI
2.74
–
11.0)
or
Cyclospora
,
though
risk
differed
by
sanitation
status
for
Cyclospora
(with
toilet
HR
1.12
95%
CI
0.69-1.80
,
without
toilet
HR
2.22
95%
CI
1.68-2.94)
.
Antiparasitic
treatment
of
Giardia
did
not
affect
the
risk
for
later
infection
with
Cyclospora
or
Cryptosporidium
. These
findings
suggest
that
Giardia
may
predispose
children
to
subsequent
infections
with
Cryptosporidium
or
Cyclospora
,
however
,
further
research
into
specific
risk
factors
such
as
specific
foods
, their
sources
, and
other
socioeconomic
risk
factors
may
help
elucidate
the
relationships
between
these
parasites
.
Language
eng
Type
Text
Format.Use
Needs Adobe Acrobat to view
Format.FileSize
298916 Bytes
OCLC number
430539327
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