Characterizing environmental factors influencing zoonotic disease reservoirs using meta-parasite prevalence

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Rights	http://www.ohsu.edu/xd/education/library/services/theses-dissertations/rights-statement.cfm
Title	Characterizing environmental factors influencing zoonotic disease reservoirs using meta-parasite prevalence
Creator.PersonalName	Mills, Cynthia L.
Thesis.Degree	M.S.
Thesis.Major	Public Health and Preventive Medicine
Thesis.DateDegreeAwarded	June 2007
Institution	Oregon Health & Science University
School	School of Medicine
Department	Dept. of Public Health and Preventive Medicine
Thesis.Advisor/Mentor	Carlson, Nicole E.
Subject.Keyword	Zoonotic Disease; Biodiversity; Hantavirus; Hantavirus Pulmonary Syndrome; Peromyscus Maniculatus
Subject.MeSH	Zoonoses Disease Reservoirs Sin Nombre virus Hantavirus Pulmonary Syndrome Biodiversity
Call Number	Q171 M657c 2007
Description.Abstract	In five parks around Portland, Oregon, where there is a dense human population, investigators have found a 5.3% prevalence of the host of the Hantavirus Pulmonary Syndrome, Sin Nombre Virus in deer mice, Peromyscus maniculatus. Previous studies show the prevalence of SNV varies inversely with the level of biodiversity measured for each reserve. The current study uses a preserved subset of 257 specimens from the same populations to examine a second disease system: gastrointestinal meta-parasites, to compare the impact of the same environmental factors on a parasite with a different transmission strategy. The results were similar: biodiversity has an inverse effect on prevalence of meta-parasites, but population densities of P. maniculatus and of all small mammals have no significant effect. Analysis was performed using GEE modeling for correlated data. Models with more than one variable tested did not retain significance suggesting that some of the effect of biodiversity can be explained by changes in population dynamics. Mass was also a significant predictor, although not in a model stratified by weight or age. Biodiversity proves to be a persistent if not robust factor influencing wildlife disease dynamics.
Language	eng
Type	Text
Format.Use	Needs Adobe Acrobat Reader to view.
Format.FileType	pdf
Format.FileSize	285 KB
OCLC number	182562454

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Characterizing environmental factors influencing zoonotic disease reservoirs using meta-parasite prevalence

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